Volume 17, Issue 4 (July 2003)

Chromosomes of some species are very small (a few microns in length), so only high magnification lenses (x100) with high aperture (typically 1.3) are used to study them. Investigators had developed methods of staining that permit chromosome identification (chromosome banding)...

Lateral force microscopy and brightfield transmission electron microscopy were utilized to distinguish between the components of a polymer nanocomposite composed of a polystyrene/polymethylmethacrylate (PS/PMMA) blend with 10% surface-treated clay. Preferential specimen preparation using cyclohexane as a selective solvent and ruthenium tetroxide as a selective staining agent for PS were used to facilitate the LFM and TEM studies respectively...

For the first time, the electron streams between crystal planes have been investigated, and clear patterns of electron streams of W(111) and W(100) are obtained with a high-resolution thermal field electron microscope (HRTFEM). Both theoretical analyses and experiment results show that the contact potential difference results in electron streams between crystal planes under an applied electric field...

Two kinds of electron-phase microscopy, Zernike phase contrast and differential interference contrast, both using phase plates, are described together with the theory of the contrast generation. Micrographs obtained by the two schemes are compared with those obtained with the scheme of defocus phase contrast most prevalent in conventional TEM...

Standard air leakage-based methods give insufficient information about paper surface topography. In this study, laser profilometry was used to measure topography directly...

Alzheimer's disease is characterized by the presence of senile plaques in the brain that are comprised primarily of the amyloid-beta peptide. Transgenic mouse models are available that develop senile plaques as they age, and are amenable for development of diagnostic techniques as well as evaluating anti-amyloid therapies that may be clinically effective...